The STOPP study(osteoarthritis progression prevention), a 2 year prospective study have demonstrated definite SYSADOA symptom modifying effect of chondroitin sulfate 800mg/day and structure modifying effect to a lesser degree SMOAD. SO, may be we can continue with chondroitin sulfate as a symptom modifying drug with no major side effects. its a good idea to check and monitor blood glucose and serum cholestrol during the first few months as there are some rare reports. May be a biochemical mri - sodium mri in a 7 T machine could enligthen us further
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